Podrobnosti o izdelku
Poglej vseISBN
9781607611318Mladinska knjiga ID
399601Leto izida
2009Datum izida
30.08.2009Velikost (šxdxv)
150 × 200 × 10Status dobavljivosti
Na zalogi pri dobaviteljuJezik
ANGTeža
300 gZaložnik
SPRINGER-VERLAG GmbHAvtor
DOMINGUEZ BENDALAOpis
Offers a comprehensive review of the development in both pancreatic development and regeneration. This book discusses the many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells in the context of potential therapeutic interventions for type I diabetes.From the discovery of Pdx1, the first 'master gene' of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.Table of Contents: Preface. Importance of the subject in the context of type I diabetes (2-3 pages) The pancreas (15 pages) Pancreatic development (50-60 pages) Pancreatic regeneration (30-40 pages) Models of regeneration Stem cells vs. beta cell replication Stem cell differentiation: general approaches (20-30 pages) Recapitulation of pancreatic development Signal-driven strategies Gene transfer and protein transduction Physiological variables Embryonic stem cells and pancreatic differentiation (40 pages) Adult stem cells and pancreatic differentiation (60 pages) Bone marrow Umbilical cord Ductal and acinar cells Mesenchymal stem cells and de-differentiation Transdifferentiation (30 pages) Remaining challenges and clinical perspectives (20-30 pages)
Pogosto kupljeno skupaj
Mladinska knjiga, Emka.si
www.emka.si
Trda
Ostali so si ogledali tudi ...
Najbolj prodajano v tem trenutku!
Najbolj prodajane, brane in aktualne knjige ta trenutek, slovenske in angleške: romani, priročniki, vodniki, potopisi, poezija, slikanice, pravljice, kartonke, uganke, stripi, otroške knjige … Novosti in uspešnice na enem mestu. V spletni knjigarni www.emka.si!
Vezava: Trda
Vezava: Broširana z zavihki
Več kot pol milijona knjig
Največja ponudba slovenskih in tujih knjig na enem mestu.
Enostaven nakup
Do izbranega le z nekaj kliki na spletu ali v eni od več kot 50 knjigarn.
Strokoven nasvet
Pred nakupom nas pokličite za nasvet ali se oglasite v knjigarni.
Vse za šolo
Nagrajena izobraževalna gradiva in kakovostne potrebščine.
Celovita ponudba za dom in pisarno
Vrhunski izdelki priznanih blagovnih znamk.
Brezplačna dostava
Brezplačna dostava za vsa naročila nad 59 € (za šolske pakete nad 140 €)
Naslov
Slovenska cesta 29, 1000 Ljubljana
E-naslovSpletna knjigarna: info@emka.si, Mladinska knjiga Založba: info@mladinska-knjiga.si
Kontakt01 241 30 00
Brezplačna številka080 12 05
- Ko izberete elemente, se celotna stran osveži.
- Odpre se v novem oknu.