Non-Invasive Monitoring of Transdermal Drug Delivery

Name: Non-Invasive Monitoring of Transdermal Drug Delivery
Brand: TAYLOR & FRANCIS BOOKS
SKU: 881507
Price: 153.76 EUR
Availability: InStock

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153,76 €

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Status dobavljivosti: 3-5 delovnih dni

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ISBN

9780367765989

Mladinska knjiga ID

881507

Leto izida

2022

Datum izida

24.03.2022

Velikost (šxdxv)

148 × 210 × 25

Status dobavljivosti

3-5 delovnih dni

Jezik

ANG

Založnik

TAYLOR & FRANCIS BOOKS

Avtor

PASQUALE ARPAIA

Opis

The book presents an innovative technology based on injection of a very weak current to trace the quantity of a drug carried immediately after the administration. The book makes the reader familiar with the technology, from the conception through the design of the instrument, up to the preliminary clinical applications. In the first chapter, the method of transdermal drug delivery and the use of impedance spectroscopy in the dermatological field are presented. The second chapter describes a screening measurement campaign aimed at proving the feasibility of the assessment method and identifying the bandwidth of interest. The prototyping, validation and characterization of an instrument to measure the amount of drug delivered (DUSM: Drug Under Skin Meter) are presented in chapter three. In the fourth chapter three experimental campaigns, based on the electrical analysis of the biological tissue behavior due to the drug delivery, are reported: (i) laboratory emulation on eggplants, (ii) ex-vivo tests on pig ears, and finally (iii) in-vivo tests on human volunteers. In the fifth chapter a behavioral model, based on Finite Elements and Partial Differential Equation, of an impedance-based measurement system for assessing the drug released under the skin, during transdermal delivering, is proposed. The last chapter is dedicated to present a campaign in order to prove the suitability for insulin therapy applications. This book is intended for biomedical engineers, biomedical engineering students, operators working in the field of biomedical instrumentation, biotechnologists, and technicians of transdermal vehiculation.